Today’s blog post will explain how to deal with the following Microsoft Outlook error “Either there is no default mail client or the current mail client cannot fulfill the messaging request. Please run Microsoft Outlook and set it as the default mail client”.
We have experienced this specific problem on Windows Xp machine equipped with Outlook 2007 that was part of Microsoft Office 2007 package. Our problem seemed to be corrupted registry key thus setting Outlook to default email sender did not resolve the issue.
After spending some time on the problem our solution was to remove PreFirstRun message from the registry to do so open registry (click start search/run “regedit” without the quotes)
In the right pane, right-click on the PreFirstRun
Select modify and remove text.